Brief description of the operation of the freeze dryer developed by Shanghai Haozhuang Instrument Co., Ltd.

Shanghai Haozhuang Instrument Co., Ltd. has developed the LNB brand freeze dryer, which is energy-saving and environmentally friendly, leading the country. Professional manufacturing is more secure and affordable. Shanghai Haozhuang has a recognized team of experts in the industry and first-class scientific and technological talents. With its profound understanding and mastery of scientific instrument technology, on the basis of independent research and development of core technology of scientific instruments, it has not only developed cryogenic instruments, ultrasonic instruments, and cabinet Instruments, microbiological instruments, ice-making refrigeration instruments, laboratory supporting instruments, and gradually formed a product pattern of various scientific instruments and technical reserve products.

The freeze drying oven is composed of a refrigeration system, a vacuum system, a heating system, and an electrical instrument control system. The main components are drying oven, condenser, freezing unit, vacuum pump, heating / cooling device, etc.

Freeze-drying (hereinafter referred to as freeze-drying) is a method of first freezing a water-containing substance into a solid state, and then sublimating the moisture from the solid state into a gaseous state to remove the water and preserve the substance. principle

There are various drying methods, such as drying, boiling, drying, spray drying and vacuum drying, but

Common drying methods are usually carried out at temperatures above 0 ° C or higher. The dried products generally have the problems of shrinking volume and hardening texture. Most of the volatile components will be lost. Some heat-sensitive substances are denatured and deactivated, and some substances even oxidize. Therefore, compared with the product before drying, there is a big difference in the characteristics of the product after drying.

Vacuum freeze drying technology, referred to as freeze drying, also known as sublimation drying. Widely used in medicine, biological products, chemical industry and food industry. For heat-sensitive substances such as antibiotics, vaccines, blood products, enzyme hormones and other biological tissues, freeze-drying technology is very suitable. The freeze-drying method is basically carried out below 0 ℃, that is, the product is frozen. Only when the residual moisture content of the product is reduced later, the product is allowed to rise to a temperature above 0 ℃, but generally does not exceed 40 ℃. Under vacuum, when the water vapor directly sublimates out, the drug remains in the ice shelf when it freezes, forming a sponge-like loose porous structure, so its volume is almost unchanged after drying. Before use again, as long as water for injection is added, it will immediately dissolve.

main application

Drug freeze-drying includes western medicine and traditional Chinese medicine. Western medicine freeze-drying has been developed in China, and many larger pharmaceutical factories have freeze-drying equipment.

In terms of Chinese medicine, it is currently limited to the lyophilization of a small amount of Chinese medicinal materials such as ginseng, velvet antler, yam, and cordyceps sinensis.

In the field of biotechnology products, freeze-drying technology is mainly used for the production of drugs such as serum, plasma, vaccines, enzymes, antibiotics, hormones; biochemical inspection drugs, immunology and bacteriology inspection drugs; blood, bacteria, arteries, bones , Long-term preservation of skin, cornea, nerve tissue and various organs.

Shanghai Haozhuang follows the principles of survival by quality, development by technology, efficiency by management, and credibility by service. It makes every set of equipment, every project, every link, strictly abides by credibility and commitment, and is willing to take the most Excellent quality and service have won the trust of users. Choose because of professionalism, Shanghai Haozhuang welcomes you, and our strong technical team will support you!

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